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Stavanger Innovation, Research and Education Networks
SIRENS Stroke
– uredde idéer som radikalt forbedrer kliniske resultater
Innovasjonsplattformen SIRENS skal sikre at SUS kan ivareta utviklingsprosjekter med stort innovasjons- og kommersialiseringspotensiale, i tett samarbeid mer andre aktører. Samarbeidene er gjerne mellom klinikk, akademia, pasientorganisasjoner og næringsliv. En slik modell piloteres gjennom SIRENS Stroke.
SIRENS Stroke leder og deltar i ulike innovasjonsprosjekter for å betydelig forbedre kliniske resultater innen slagbehandling. Disse prosjektene er innenfor kvalitetsforbedring, simulering, og tjeneste- og produktutvikling.
Gjennom dedikert bruk av simuleringstrening har klinikken blant annet redusert door-to-needle tid fra 29 minutter til 13 minutter. Les mer under prosjekter og nyheter.
Fjetland L, Roy S, Kurz KD, Larsen JP, Kurz MW. Endovascular acute stroke treatment performed by vascular interventional radiologists, is it safe and efficacious? Cardiovasc Intervent Radiol. 2012 Oct;35(5):1029-35. LINK: https://link.springer.com/article/10.1007%2Fs00270-012-0438-5
Fjetland L, Kurz MW. Encouraging and positive trend towards treatment of acute ischemic stroke performed by vascular interventional radiologist: reply. Cardiovasc Intervent Radiol. 2014 Oct;37(5):1387-8. LINK: https://link.springer.com/article/10.1007%2Fs00270-014-0863-8
Bhan A, Advani R, Kurz KD, Farbu E, Kurz MW. Wernicke's Encephalopathy Mimicking Acute Onset Stroke Diagnosed by CT Perfusion. Case Rep Neurol Med. 2014;2014:673230. doi: 10.1155/2014/673230. Epub 2014 Feb 23. LINK: https://www.hindawi.com/journals/crinm/2014/673230/
Logallo N, Kvistad CE, Nacu A, Naess H, Waje-Andreassen U, Asmuss J, Aamodt AH, Lund C, Kurz MW, Rønning OM, Salvesen R, Idicula TT, Thomassen L. The Norwegian tenecteplase stroke trial (NOR-TEST): randomised controlled trial of tenecteplase vs. alteplase in acute ischaemic stroke. BMC Neurol. 2014 May 15;14:106. doi: 10.1186/1471-2377-14-106. LINK: https://bmcneurol.biomedcentral.com/articles/10.1186/1471-2377-14-106
Advani R, Naess H, Kurz MW. Evaluation of the implementation of a rapid response treatment protocol for patients with acute onset stroke: can we increase the number of patients treated and shorten the time needed? Cerebrovasc Dis Extra. 2014 Jun 6;4(2):115-21. LINK: https://www.karger.com/Article/FullText/363050
Fjetland L, Kurz KD, Roy S, Kurz MW. Evaluation of the recombinant tissue plasminogen activator pretreatment in acute stroke patients with large vessel occlusions treated with the direct bridging approach. Is it worth the effort? Eur J Neurol. 2015 Feb;22(2):322-7. LINK: https://onlinelibrary.wiley.com/doi/full/10.1111/ene.12569
Odland A, Saervoll P, Advani R, Kurz MW, Kurz KD. Are the current MRI criteria using the DWI-FLAIR mismatch concept for selection of patients with wake-up stroke to thrombolysis excluding too many patients? Scand J Trauma Resusc Emerg Med. 2015 Feb 19;23:22. LINK: https://sjtrem.biomedcentral.com/articles/10.1186/s13049-015-0101-7
Næss H, Kurz M, Thomassen L, Waje-Andreassen U. Serial NIHSS scores in patients with acute cerebral infarction. Acta Neurol Scand 2015: SEP 2015; DOI: 10.1111/ane.1247. LINK: https://onlinelibrary.wiley.com/doi/full/10.1111/ane.12477
Kurz MW, Advani R, Behzadi G, Eldoen G, Farbu E, Kurz KD. Wake up stroke – amendable for thrombolysis like stroke with known onset time? Acta Neurol Scand. 2016 Sep 18. doi: 10.1111/ane.12686. LINK: https://onlinelibrary.wiley.com/doi/full/10.1111/ane.12686
Logallo N, Novotny V, Assmus J, Kvistad CE, Alteheld L, Rønning OM, Thommessen B, Amthor KF, Ihle-Hansen H, Kurz M, Tobro H, Kaur K, Stankiewicz M, Carlsson M, Morsund Å, Idicula T, Aamodt AH, Lund C, Næss H, Waje-Andreassen U, Thomassen L. Tenecteplase versus alteplase for management of acute ischaemic stroke (NOR-TEST): a phase 3, randomised, open-label, blinded endpoint trial. Lancet Neurol. Volume 16, Issue 10, October 2017, Pages 781-788 LINK:https://www.sciencedirect.com/science/article/abs/pii/S1474442217302533?via%3Dihub
Rezai MK, Advani R, Dalen I, Fjetland L, Kurz KD, Kurz MW. Endovascular Thrombectomy in the Elderly: Do Radiological and Clinical Outcomes Differ from Those in Younger Patients? A Prospective Single-Center Experience. Cerebrovasc Dis. 2019 Feb 26;47(1-2):65-71. LINK:https://www.karger.com/Article/Abstract/497315
Ratajcek-Tretel B, Lambert AT, Johansen H et al., Atrial fibrillation in cryptogenic stroke and transient ischaemic attack – The Nordic Atrial Fibrillation and Stroke (Nor-FIB) Study: Rationale and design. European stroke Journal European Stroke Journal 2019 0(0) 1–9 LINK: https://journals.sagepub.com/doi/10.1177/2396987319837089
Kvistad EK, Novotny V, Kurz MW, Ronning OM, Thommessen B, Carlsson M, Waje Andreassen UW, Naess H, Thomassen L, Logallo N. Safety and outcomes of tenecteplase in moderate and severe ischemic stroke - Results from NOR-TEST. Stroke. 2019 May;50(5):1279-1281. LINK: https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.025041
Ajmi SC, Advani R, Fjetland L, Kurz KD, Lindner T, Qvindesland SA, Ersdal H, Goyal M, Kvaløy JT, Kurz M. Reducing door-to-needle times in stroke thrombolysis to 13 min through protocol revision and simulation training: a quality improvement project in a Norwegian stroke centre. BMJ Quality & Safety 2019; 28 862-865 Jun 29. LINK: https://qualitysafety.bmj.com/content/28/11/939
Hvilke prosjekter deltar vi i?
Hjerneslag er en viktig årsak til invaliditet og dødelighet i hele verden. Årlig rammes nesten 15 000 nordmenn – rundt 40 om dagen – og man antar at mer enn 70 000 mennesker lever med betydelige plager og skader etter slag her i landet. Hjerneslag er en av de store folkesykdommene og en stor utfordring for alle ledd i helsevesenet. Særlig geografisk og behandlingstiden er avgjørende for hvor store skadefølger pasienten får.
SIRENS Stroke leder og deltar i ulike innovasjonsprosjekter for å forbedre kliniske resultater. Disse prosjektene er innenfor kvalitetsforbedring, simulering, og tjeneste- og produktutvikling.
